This poster documents LECO's development of gas chromatography time-of-flight mass spectrometry methods for the characterization of derivated urine samples.

Enhanced Metabolite Profiling: Hardn and Soft Ionization High Resolution Time-of-Flight Mass Spetrometry | Pegasus GC-HRT | 203-821-447

Utilization of Statistical Compare Software and FisherRatios Prior to Multivariate Analysis for Complex GCxGC-TOFMS Data in Order to Define Statistical Variatio nBetween the Small Molecule Metabolite Profiles ofDifferent Fish Species

How Comprehensive is Your Analysis? Human Molecular Profiling Using High Resolution Time-of-Flight Mass Spectrometry | Pegasus GC-HRT | 203-821-503

Application of GC High Resolution Time-of-Flight Mass Spectrometry to Mouse Liver Metabolomic Analyses

Metabolomic Profiling of Corn and Rice Extracts Using a Benchtop GC-TOFMS | Pegasus BT | 203-821-526

A Comprehensive GC-TOFMS Metabolomics Workflow | Pegasus BT and ChromaTOF Sync | 203-821-662

Analysis of Smoker's and Non-Smoker's Urine Using the Pegasus BT 4D | 203-821-557

Comprehensive Characterization of Green Leaf Tobacco Extracts Using GC-HRT

Utilizing the Pegasus GC-HRT 4D for Improved Yeast Metabolite Characterization | Pegasus GC-HRT 4D | 203-821-502

This curated compilation of articles and papers illustrates how Time-of-Flight Mass Spectrometry is advancing metabolomics research. Laboratories around the world use the Pegasus series of mass spectrometers to help their data soar.

Chemical constituents on their wings provide cicadas with water resistance as well and antimicrobial, anti-reflective, and self-cleaning functions. In this study, the wing chemicals of two cicada species were examined using the Pegasus® BT 4D GCxGC-TOFMS system and analyzed through the ChromaTOF® software.

Infection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can lead to severe respiratory tract damage and acute lung injury. Scientists performed untargeted metabolomics analysis using the Pegasus BT 4D GCxGC-TOF-MS on exhaled breath condensate from COVID-19 patients.

Food authentication protects consumers, sellers, and producers from fraud. In this article, scientists discuss new non-destructive methods of food authentication which utilizes LECO Pegasus® BT 4D GCxGC-TOFMS and ChromaTOF® software to enhance cultivar classification.

In this article from The Analytical Scientist (Issue #90, September 2020), the value of two-dimensional gas chromatography high-resolution time-of-flight mass spectrometry (GCxGC-HRTOFMS) to metabolomics, breathomics, and other -omics fields of study, are examined.

Bob Nelson and Chris Reddy [Woods Hole Oceanographic Institution (WHOI)] discuss their laboratory's GCxGC process. Presented 19 September 2017.

Metabolomics. LECO Reference # TR ISCC17 LPSS-218

Metabolomics. LECO Reference # JH ISCCE13 LPSS-109

Metabolomics. LECO Reference # DA ISCCE13 LPSS-113

This poster demonstrates the process taken to analyze blood serum with GCxGC-TOF-MS methods to measure effects of traumatic brain injuries.

2014

Copresenters Renee Cataneo & Mayur Mundada [Menssana Research Inc.] discuss data obtained through GCxGC TOF-MS analysis of breath samples. Originally presented 20 September 2012.

Metabolomics. LECO Reference # JP BA2014 LPSS-157

Metabolomics. LECO Reference # JB ASMS11 LPSS-036

Two-dimensional comprehensive gas chromatography analysis of lipophilac soxhlet extractions supplied by the USDA Forest Service.

Metabolomics. LECO Reference # MG ASMS09 LPSS-003

Metabolomics. LECO Reference # JH Pcon09 LPSS-008

Metabolomics. LECO Reference # JH Pcon10 LPSS-017

Dr. Heather Bean, Arizona State University, discusses using GCxGC-TOF MS to detect and phenotype infections directly from lung samples.

Metabolomics. LECO Reference # SP ASMS09 LPSS-006

Metabolomics. LECO Reference # JP ASMS13 LPSS-122

Non-alcoholic fatty liver disease (NAFLD) is a major medical issue in developed countries. In this investigation, researchers compared single-dimensional and two-dimensional gas chromatography methods to identify NAFLD biomarkers.

St. Louis Metabolomics Symposium Presentation

Vladimir Tolstikov, PhD, from Eli Lilly, discusses utilizing High-Resolution Gas Chromatography Mass Spectrometry in Metabolomics analyses. Originally presented 21 February 2013.

St. Louis Metabolomics Symposium Presentation

LECO and Berkeley Lab Partner for Metabolomics Advancements

Reference Library developed by LECO and Dr. Oliver Fiehn (University of California-Davis). Over 1,100 spectra of 700 metabolites available for sample and data comparison of chromatograms. This metabolomics reference library is fully integrated into the ChromaTOF® software suite. LECO Ref. #209-207

St. Louis Metabolomics Symposium Presentation

Metabolomics. LECO Reference # JH Pcon LPSS-022

Solutions for Metabolomics Analysis. As the established leader in GC-MS metabolomics, LECO products deliver the accuracy, resolving power, deconvoclution, and speed to characterize the most complex biological systems. LECO Ref. #209-240

Metabolomics. LECO Reference # JH ASMS09 LPSS-007

Metabolomics. LECO Reference # JH ASMS11 LPSS-040

Metabolomics. LECO Reference # JP ASMS LPSS-151

Metabolomics. LECO Reference # JP ASMS14 LPSS-153

Metabolomics. LECO Reference # DA RIVA14 LPSS-132

Metabolomics. LECO Reference # LHF Pcon13 LPSS-100

Metabolomics. LECO Reference # DA ASMS13 LPSS-124

Presented at St. Louis Metabolomics Symposium

Metabolomics. LECO Reference # DA MBX16 LPSS-193

Metabolomics. LECO Reference # JH ASMS13 LPSS-120